Journal Issue: Bioinform Biol Insights Volume 18;  2024

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Journal List

Volume 18;  2024

Original Research Article

Phylogenetic Characterization of Resistant Salmonella Strains in Typhoid Fever Patients in Nigeria
Olukayode Olugbenga Orole, Jebes Ngolo Lamini, Aleruchi Chuku
Bioinform Biol Insights. 2024; 18: 11779322231220194. Published online 2024 Jan 9. doi: 10.1177/11779322231220194
PMCID:
PMC10777790
Abstract Article PDF–735K
Neomangiferin, a Naturally Occurring Mangiferin Congener, Inhibits Sodium-Glucose Co-transporter-2: An In silico Approach
Ayobami J Olusola, Samson O Famuyiwa, Kolade O Faloye, Oluwaseun E Olatunji, Uduak I Olayemi, Abiodun A Adeyemi, John O Balogun, Seun B Ogundele, Blessing O Babamuyiwa, Rajesh B Patil
Bioinform Biol Insights. 2024; 18: 11779322231223851. Published online 2024 Jan 17. doi: 10.1177/11779322231223851
PMCID:
PMC10798119
Abstract Article PDF–2.2M

Review

Evaluation of the Antidiabetic Activities of the Fruit of Parquetina nigrescens (Afzel.) Bullock and In Silico Identification of Its Antidiabetic Agent
Marcus D Ayoola, Yetunde B Ogundeko, Temiloluwa D Obanleowo, Deborah O Omole, Blessing N Chukwu, Kolade O Faloye
Bioinform Biol Insights. 2024; 18: 11779322231223857. Published online 2024 Jan 26. doi: 10.1177/11779322231223857
PMCID:
PMC10822077
Abstract Article PDF–1.6M

Original Research Article

Revealing Propolis Potential Activity on Inhibiting Estrogen Receptor and Heat Shock Protein 90 Overexpressed in Breast Cancer by Bioinformatics Approaches
Masriana Vivi Simanjuntak, Muhammad Miftah Jauhar, Putri Hawa Syaifie, Adzani Gaisani Arda, Etik Mardliyati, Wervyan Shalannanda, Beni Rio Hermanto, Isa Anshori
Bioinform Biol Insights. 2024; 18: 11779322231224187. Published online 2024 Jan 24. doi: 10.1177/11779322231224187
PMCID:
PMC10809879
Abstract Article PDF–2.9M
Comparative Transcriptomics Data Profiling Reveals E2F Targets as an Important Biological Pathway Overexpressed in Intellectual Disability Disorder
Prekshi Garg, Farrukh Jamal, Prachi Srivastava
Bioinform Biol Insights. 2024; 18: 11779322231224665. Published online 2024 Feb 13. doi: 10.1177/11779322231224665
PMCID:
PMC10865946
Abstract Article PDF–1.0M
Functional Enrichment Analysis of Tumor Microenvironment–Driven Molecular Alterations That Facilitate Epithelial-to-Mesenchymal Transition and Distant Metastasis
Mahnaz Abdolahi, Parnian Ghaedi Talkhounche, Mohammad Hossein Derakhshan Nazari, Haniyeh Sadat Hosseininia, Niloofar Khoshdel-Rad, Amin Ebrahimi Sadrabadi
Bioinform Biol Insights. 2024; 18: 11779322241227722. Published online 2024 Feb 4. doi: 10.1177/11779322241227722
PMCID:
PMC10840405
Abstract Article PDF–2.5M
Computational Studies on 6-Pyruvoyl Tetrahydropterin Synthase (6-PTPS) of Plasmodium falciparum
Shalom N Chinedu, Mercy Bella-Omunagbe, Esther Okafor, Rufus Afolabi, Ezekiel Adebiyi
Bioinform Biol Insights. 2024; 18: 11779322241230214. Published online 2024 Feb 7. doi: 10.1177/11779322241230214
PMCID:
PMC10851736
Abstract Article PDF–1.4M
Human Pose Estimation for Clinical Analysis of Gait Pathologies
Manal Mostafa Ali, Maha Medhat Hassan, M Zaki
Bioinform Biol Insights. 2024; 18: 11779322241231108. Published online 2024 May 15. doi: 10.1177/11779322241231108
PMCID:
PMC11097739
Abstract Article PDF–3.0M
Effectiveness of Narciclasine in Suppressing the Inflammatory Response in Sepsis: Molecular Docking and In Silico Studies
Manoj Kumar Kingsley, Gurugubelli Krishna Rao, Ballambattu Vishnu Bhat
Bioinform Biol Insights. 2024; 18: 11779322241233436. Published online 2024 Mar 16. doi: 10.1177/11779322241233436
PMCID:
PMC10943728
Abstract Article PDF–3.3M

Review

Drought Stress Amelioration Attributes of Plant-Associated Microbiome on Agricultural Plants
Victor Funso Agunbiade, Olubukola Oluranti Babalola
Bioinform Biol Insights. 2024; 18: 11779322241233442. Published online 2024 Mar 8. doi: 10.1177/11779322241233442
PMCID:
PMC10924568
Abstract Article PDF–650K

Original Research Article

Enzymatic Performance of Aspergillus oryzae α-Amylase in the Presence of Organic Solvents: Activity, Stability, and Bioinformatic Studies
Khomaini Hasan, Umi Baroroh, Indri Novia Madhani, Zahra Silmi Muscifa, Mia Tria Novianti, Muhamad Abidin, Muhammad Yusuf, Toto Subroto
Bioinform Biol Insights. 2024; 18: 11779322241234767. Published online 2024 Apr 23. doi: 10.1177/11779322241234767
PMCID:
PMC11041543
Abstract Article PDF–1.8M
Investigating D-Amino Acid Oxidase Expression and Interaction Network Analyses in Pathways Associated With Cellular Stress: Implications in the Biology of Aging
V Kalidasan, Darshinie Suresh, Nurulisa Zulkifle, Yap Siew Hwei, Leong Kok Hoong, Reena Rajasuriar, Kumitaa Theva Das
Bioinform Biol Insights. 2024; 18: 11779322241234772. Published online 2024 Feb 28. doi: 10.1177/11779322241234772
PMCID:
PMC10903195
Abstract Article PDF–2.0M
Computer-Assisted Discovery of Salvia fruticosa Compounds With Schistosomicidal Activity
Ryman Shoko, Farirai Mandivenga
Bioinform Biol Insights. 2024; 18: 11779322241240651. Published online 2024 Mar 27. doi: 10.1177/11779322241240651
PMCID:
PMC10976507
Abstract Article PDF–1.7M
Integrating Network Pharmacology and Molecular Docking Approach to Elucidate the Mechanism of Commiphora wightii for the Treatment of Rheumatoid Arthritis
Mostafa A Abdel-Maksoud, Mostafa A Askar, Ibrahim Y Abdel-rahman, Mustafa Gharib, Mohammed Aufy
Bioinform Biol Insights. 2024; 18: 11779322241247634. Published online 2024 May 18. doi: 10.1177/11779322241247634
PMCID:
PMC11102677
Abstract Article PDF–1.7M
In Silico Study, Protein Kinase Inhibition and Molecular Docking Study of Benzimidazole Derivatives
Kamaraj Karthick, Kamaraj Abishek, Ebenezer Angel Jemima
Bioinform Biol Insights. 2024; 18: 11779322241247635. Published online 2024 Jun 6. doi: 10.1177/11779322241247635
PMCID:
PMC11159556
Abstract Article PDF–1.7M

Research Article

The Potential Role of Phytochemicals of Juniperus procera in the Treatment of Ovarian Cancer and the Inhibition of Human Topoisomerase II Alpha Activity
Ateeq A Al-Zahrani
Bioinform Biol Insights. 2024; 18: 11779322241248904. Published online 2024 Apr 25. doi: 10.1177/11779322241248904
PMCID:
PMC11047251
Abstract Article PDF–899K

Original Research Article

In Silico Identification and Characterization of Fatty Acid Desaturase (FAD) Genes in Argania spinosa L. Skeels: Implications for Oil Quality and Abiotic Stress
Abdelmoiz El Faqer, Karim Rabeh, Mohammed Alami, Abdelkarim Filali-Maltouf, Bouchra Belkadi
Bioinform Biol Insights. 2024; 18: 11779322241248908. Published online 2024 May 5. doi: 10.1177/11779322241248908
PMCID:
PMC11072076
Abstract Article PDF–4.9M

Research Article

The Novel PTX3 Variant g.22645332G>T Is Strongly Related to Awassi and Hamdani Sheep Litter Size
Faris S Imran, Tahreer M Al-Thuwaini
Bioinform Biol Insights. 2024; 18: 11779322241248912. Published online 2024 Apr 25. doi: 10.1177/11779322241248912
PMCID:
PMC11047254
Abstract Article PDF–983K

Short Communication

Analysis of CENP-B Boxes as Anchor of Kinetochores in Centromeres of Human Chromosomes
Fritz F Parl
Bioinform Biol Insights. 2024; 18: 11779322241248913. Published online 2024 Apr 29. doi: 10.1177/11779322241248913
PMCID:
PMC11060027
Abstract Article PDF–808K

Original Research Article

Integration of Multi-Omics Data for the Classification of Glioma Types and Identification of Novel Biomarkers
Francisca G Vieira, Regina Bispo, Marta B Lopes
Bioinform Biol Insights. 2024; 18: 11779322241249563. Published online 2024 May 27. doi: 10.1177/11779322241249563
PMCID:
PMC11135104
Abstract Article PDF–1.4M

Research Article

Genes Differentially Expressed Across Major Arteries Are Enriched in Endothelial Dysfunction-Related Gene Sets: Implications for Relative Inter-artery Atherosclerosis Risk
Paul A Brown
Bioinform Biol Insights. 2024; 18: 11779322241251563. Published online 2024 May 16. doi: 10.1177/11779322241251563
PMCID:
PMC11100403
Abstract Article PDF–9.8M

Original Research Article

DENV-2 Outbreak Associated With Cosmopolitan Genotype Emergence in Western Brazilian Amazon
Jessiane Rodrigues Ribeiro, Tárcio Peixoto Roca, Gleense dos Santos Cartonilho, Ana Maísa Passos-Silva, Hillquias Monteiro Moreira, Karolaine Santos Teixeira, André Luiz Ferreira da Silva, Celina Aparecida Bertoni Lugtenburg, Alcione Oliveira dos Santos, Juan Miguel Villalobos Salcedo, Valdinete Alves do Nascimento, Victor Costa de Souza, Rosemary Aparecida Roque, Marco Aurélio Krieger, Felipe Gomes Naveca, Rita de Cássia Pontello Rampazzo, Deusilene Souza Vieira
Bioinform Biol Insights. 2024; 18: 11779322241251581. Published online 2024 May 11. doi: 10.1177/11779322241251581
PMCID:
PMC11088811
Abstract Article PDF–1.9M

Research Article

Investigating the Antimicrobial Effects of a Novel Peptide Derived From Listeriolysin S on S aureus, E coli, and L plantarum: An In Silico and In Vitro Study
Mojgan Sarabi Nobakht, Kaveh Bazyar, Mohammad Sadegh Ghalyanchi Langeroudi, Mandana Mirzaei, Mehdi Goudarzi, Ali Shivaee
Bioinform Biol Insights. 2024; 18: 11779322241252513. Published online 2024 May 15. doi: 10.1177/11779322241252513
PMCID:
PMC11100392
Abstract Article PDF–920K

Original Research Article

Identification of Molecular Mechanisms of Ameloblastoma and Drug Repositioning by Integration of Bioinformatics Analysis and Molecular Docking Simulation
Suthipong Chujan, Nutsira Vajeethaveesin, Jutamaad Satayavivad, Nakarin Kitkumthorn
Bioinform Biol Insights. 2024; 18: 11779322241256459. Published online 2024 May 28. doi: 10.1177/11779322241256459
PMCID:
PMC11135093
Abstract Article PDF–1.8M

Current and Prospective Immunoinformatic Approaches to Design Drug and Vaccine Candidates

Research Article

Immunoinformatics-Based Design of Multi-epitope DNA and mRNA Vaccines Against Zika Virus
Juciene de Matos Braz, Marcus Vinicius de Aragão Batista
Bioinform Biol Insights. 2024; 18: 11779322241257037. Published online 2024 May 31. doi: 10.1177/11779322241257037
PMCID:
PMC11143849
Abstract Article PDF–2.1M

Research Articles

Targeting decaprenylphosphoryl-β-D-ribose 2′-epimerase for Innovative Drug Development Against Mycobacterium Tuberculosis Drug-Resistant Strains
Ghyzlane EL Haddoumi, Mariam Mansouri, Jouhaina Kourou, Lahcen Belyamani, Azeddine Ibrahimi, Ilham Kandoussi
Bioinform Biol Insights. 2024; 18: 11779322241257039. Published online 2024 May 28. doi: 10.1177/11779322241257039
PMCID:
PMC11135120
Abstract Article PDF–3.8M
Rapid Targeted Assembly of the Proteome Reveals Evolutionary Variation of GC Content in Avian Lice
Avery R Grant, Kevin P Johnson, Edward L Stanley, James Baldwin-Brown, Stanislav Kolenčík, Julie M Allen
Bioinform Biol Insights. 2024; 18: 11779322241257991. Published online 2024 Jun 9. doi: 10.1177/11779322241257991
PMCID:
PMC11163934
Abstract Article PDF–2.8M

Original Research Article

Classification of Long Non-Coding RNAs s Between Early and Late Stage of Liver Cancers From Non-coding RNA Profiles Using Machine-Learning Approach
Songtham Anuntakarun, Jakkrit Khamjerm, Pisit Tangkijvanich, Natthaya Chuaypen
Bioinform Biol Insights. 2024; 18: 11779322241258586. Published online 2024 Jun 5. doi: 10.1177/11779322241258586
PMCID:
PMC11155358
Abstract Article PDF–1.8M

Research Article

Identification of an Allele-Specific Transcription Factor Binding Interaction that May Regulate PLA2G2A Gene Expression
Aki Hara, Eric Lu, Laurel Johnstone, Michelle Wei, Shudong Sun, Brian Hallmark, Joseph C Watkins, Hao Helen Zhang, Guang Yao, Floyd H Chilton
Bioinform Biol Insights. 2024; 18: 11779322241261427. Published online 2024 Jul 30. doi: 10.1177/11779322241261427
PMCID:
PMC11287738
Abstract Article PDF–1.0M

Original Research Article

Machine Learning-Based Approach to Identify Inhibitors of Sterol-14-Alpha Demethylase: A Study on Chagas Disease
Jamiyu A Saliu
Bioinform Biol Insights. 2024; 18: 11779322241262635. Published online 2024 Jul 30. doi: 10.1177/11779322241262635
PMCID:
PMC11287730
Abstract Article PDF–1.0M

Research Article

Devising Isolation Forest-Based Method to Investigate the sRNAome of Mycobacterium tuberculosis Using sRNA-seq Data
Upasana Maity, Ritika Aggarwal, Rami Balasubramanian, Divya Lakshmi Venkatraman, Shubhada R Hegde
Bioinform Biol Insights. 2024; 18: 11779322241263674. Published online 2024 Jul 30. doi: 10.1177/11779322241263674
PMCID:
PMC11292719
Abstract Article PDF–3.6M

Current and Prospective Immunoinformatic Approaches to Design Drug and Vaccine Candidates

Research Articles

Computational Exploration of Berberis lycium Royle: A Hidden Treasure Trove for Antiviral Development
Mamuna Mukhtar, Haris Ahmed Khan, Tope Abraham Ibisanmi, Ayodele Ifeoluwa Faleti, Najam us Sahar Sadaf Zaidi
Bioinform Biol Insights. 2024; 18: 11779322241264144. Published online 2024 Jul 27. doi: 10.1177/11779322241264144
PMCID:
PMC11283669
Abstract Article PDF–2.8M
Antiviral Activity, Pharmacoinformatics, Molecular Docking, and Dynamics Studies of Azadirachta indica Against Nipah Virus by Targeting Envelope Glycoprotein: Emerging Strategies for Developing Antiviral Treatment
Otun Saha, Noimul Hasan Siddiquee, Rahima Akter, Nikkon Sarker, Uditi Paul Bristi, Khandokar Fahmida Sultana, SM Lutfor Rahman Remon, Afroza Sultana, Tushar Ahmed Shishir, Md Mizanur Rahaman, Firoz Ahmed, Foysal Hossen, Mohammad Ruhul Amin, Mir Salma Akter
Bioinform Biol Insights. 2024; 18: 11779322241264145. Published online 2024 Jul 27. doi: 10.1177/11779322241264145
PMCID:
PMC11283663
Abstract Article PDF–2.3M

Research Articles

Elucidation of the CadA Protein 3D Structure and Affinity for Metals
Rajkumar Prabhakaran, Rajkumar Thamarai
Bioinform Biol Insights. 2024; 18: 11779322241266701. Published online 2024 Aug 8. doi: 10.1177/11779322241266701
PMCID:
PMC11311160
Abstract Article PDF–7.4M
Nilotinib: Disrupting the MYC-MAX Heterocomplex
Kamilla Shah, Maham Ansari, Samina Saeed, Abdul Wali, Muhammad Mushtaq Yasinzai
Bioinform Biol Insights. 2024; 18: 11779322241267056. Published online 2024 Jul 29. doi: 10.1177/11779322241267056
PMCID:
PMC11287739
Abstract Article PDF–2.8M
Reproduction of Awassi and Hamdani Sheep Is Associated With a Novel Missense SNP (p.24Ile>Thr) of the GnIH Gene
Waleed A Abd Al-Jabar, Tahreer M Al-Thuwaini
Bioinform Biol Insights. 2024; 18: 11779322241267188. Published online 2024 Aug 5. doi: 10.1177/11779322241267188
PMCID:
PMC11304492
Abstract Article PDF–982K
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