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Search life-sciences literature ( articles, preprints and more)

Journal Issue: Antib Ther Volume 7(3); 2024 Jul

Journal List

Volume 7(3); 2024 Jul

Research Articles

A case study of a bispecific antibody manufacturability assessment and optimization during discovery stage and its implications

Shuang Wang, Weijie Zhang, Baotian Yang, Xudong Zhang, Jing Fang, Haopeng Rui, Zhijian Chen, Jijie Gu, Zhiqiang Chen, Jianqing Xu

Antib Ther. 2024 Jul; 7(3): 189–198. Published online 2024 May 29. doi: 10.1093/abt/tbae013

PMCID:: PMC11259756

Abstract Article PDF–746K

Fc engineering by monoclonal mammalian cell display for improved affinity and selectivity towards FcγRs

Zening Wang, Minhyo Kang, Afshin Ebrahimpour, Chuan Chen, Xin Ge

Antib Ther. 2024 Jul; 7(3): 209–220. Published online 2024 Jun 21. doi: 10.1093/abt/tbae017

PMCID:: PMC11259757

Abstract Article PDF–2.0M

Artificial Intelligence in antibody discovery, development and beyond

Protein language models enable prediction of polyreactivity of monospecific, bispecific, and heavy-chain-only antibodies

Xin Yu, Kostika Vangjeli, Anusha Prakash, Meha Chhaya, Samantha J Stanley, Noah Cohen, Lili Huang

Antib Ther. 2024 Jul; 7(3): 199–208. Published online 2024 May 30. doi: 10.1093/abt/tbae012

PMCID:: PMC11259759

Abstract Article PDF–1.0M

Articles from Antibody Therapeutics are provided here courtesy of Oxford University Press